Barbiturates

Barbiturates are a class of around 12 compounds derived from barbituric acid. They are central nervous system depressants that can be used as sedatives, hypnotics, anaesthetics or anti-epileptic drugs. Barbiturates can be divided into three main groups according to their duration of action. The ultrashort-acting barbiturates are used clinically as anaesthetics whilst the long-acting barbiturates have anti-convulsing properties. Short-acting compounds can be used as hypnotics and favoured by drug abusers due to their ability to reduce tension and produce a feeling of tranquillity. An overdose of barbiturates can lead to a dramatic fall in blood pressure and body temperature, depressed respiration or coma.

Product Number: BAR10004

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AnalyteLODMatricesCompoundsCross Reactivity %
Barbiturates17.3 ng/mL
Whole Blood, Post Mortem Blood, UrinePhenobarbital100
Secobarbital184.7
Cyclopentobarbital132.8
Amobarbital109.9
Butabarbital77.5
Pentobarbital76.5
Butalbital32.1
Barbital20.5
Hexobarbital<1
*LOD is standardised to this compound