Barbiturates are a class of around 12 compounds derived from barbituric acid. They are central nervous system depressants that can be used as sedatives, hypnotics, anaesthetics or anti-epileptic drugs. Barbiturates can be divided into three main groups according to their duration of action. The ultrashort-acting barbiturates are used clinically as anaesthetics whilst the long-acting barbiturates have anti-convulsing properties. Short-acting compounds can be used as hypnotics and favoured by drug abusers due to their ability to reduce tension and produce a feeling of tranquillity. An overdose of barbiturates can lead to a dramatic fall in blood pressure and body temperature, depressed respiration or coma.
Product Number: BAR10004
Analyte | LOD | Matrices | Compounds | Cross Reactivity % |
---|---|---|---|---|
Barbiturates | 17.3 ng/mL | Whole Blood, Post Mortem Blood, Urine | Phenobarbital | 100 |
Secobarbital | 184.7 | |||
Cyclopentobarbital | 132.8 | |||
Amobarbital | 109.9 | |||
Butabarbital | 77.5 | |||
Pentobarbital | 76.5 | |||
Butalbital | 32.1 | |||
Barbital | 20.5 | |||
Hexobarbital | <1 |