Dextromethorphan

Dextromethorphan is the d-isomer of 3-methoxy-N-methylmorphinan, a synthetic analogue of codeine. It is found in numerous cough syrups, tablets and capsules as the hydrobromide salt in amounts of 2.5-30 mg/dosage unit. At the recommended dosages, dextromethorphan is a safe drug. However, at higher dosages, it can have euphoric, stimulant and dissociative effects. It has been reported that abuse of this drug among adolescents has become widespread. Some known side effects of dextromethorphan abuse can include confusion, dizziness, double or blurred vision, slurred speech abdominal pain, nausea and vomiting, rapid heartbeat, drowsiness and hallucinations.

Product Number: DX3497

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Cross Reactivity

AnalyteLODMatricesCompoundsCross Reactivity %
Dextromethorphan1.64 ng/mLWhole Blood, Post Mortem Blood, UrineDextromethorphan hydrobromide monohydrate100
Dextrorphan43.2
(±)-nordextromethorphan16
(+)-3-hydroxymorphinan hydrobromide0.8
(+)-3-methoxymorphinan hydrochloride0.1
N-desmethyldextrorphan0.1
*LOD is standardised to this compound