Synthetic Cannabinoids (JWH-018/AM-2201)

JWH-018, a Synthetic Cannabinoid, is also commonly referred to as ‘spice’.  Initial studies of the metabolism of JWH have highlighted metabolic processes such as ring and alkyl substituent hydroxylation, carboxylation and glucuronidation1. Recently a number of countries in Europe, as well as in the US and Canada have banned the use of these substances.

Product Number: SC3474

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AnalyteLODMatricesCompoundsCross Reactivity
Synthetic Cannabinoids (JWH-018/AM-2201)2.5Urine, Whole bloodJWH-018100
JWH-073 N-(4-hydroxybutyl) metabolite255
JWH-018 N-(5-hydroxypentyl) metabolite231
JWH 018 N-(3-methylbutyl) isomer (JWH-073 3-methylbutyl homologue)217
6-OH JWH-018 (JWH-018 6-hydroxyindole metabolite)215
JWH-018 (5'-Carboxy)206
(±)-JWH 018 N-(4-hydroxypentyl) metabolite195
AM-1220179
AM-2201 N-(4-fluoropentyl) isomer176
JWH-073 N-(3-hydroxybutyl) metabolite164
6-OH JWH-073 (JWH-073 6-hydroxyindole metabolite)162
AM-2201 N-(4-hydroxypentyl) metabolite145
JWH-073135
5-OH JWH-073 (JWH-073 5-hydroxyindole metabolite)135
JWH-018 (1-(4-Carboxybutyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone (N-carboxybutyl)133
JWH-200 6-hydroxyindole metabolite133
WIN 55,225 (other name JWH-200)127
AM-2201119
7-OH JWH-073 (JWH-073 7-hydroxyindole metabolite)113
JWH 073 N-(2-methylpropyl) isomer113
JWH-022102
JWH-073 N-Butanol96
JWH-018 6-methoxyindole analogue95
7-OH JWH-018 (JWH-018 7-hydroxyindole metabolite)89
JWH-018 N-pentanoic acid metabolite85
JWH-018 N-(2-methylbutyl) isomer (JWH-073 2-methylbutyl homologue)78
JWH 018 N-(1,2-dimethylpropyl) isomer70
JWH-200 5-hydroxyindole metabolite63
JWH-018 N-(2,2-dimethylpropyl) isomer62
5-OH JWH-018 (JWH-018 5-hydroxyindole metabolite)56
JWH-018 N-(1-methylbutyl) isomer54
JWH-073 4 Butanoic Acid38
JWH 019 5-hydroxyindole metabolite (JWH-019-M2)38
JWH-073 N-Butanoic acid metabolite37
JWH-398 N-(5-hydroxypentyl) metabolite36
JWH-01935
JWH-02022
JWH-122 N-(5-hydroxypentyl) metabolite16
4-OH JWH-073 (JWH-073 4-hydroxyindole metabolite)15
JWH 073 2-methylnaphthyl analogue14
JWH 122 7-methylnaphthyl isomer13
JWH 122 2-methylnaphthyl isomer12
JWH-39812
JWH-073 4-methylnaphthyl analogue10
JWH-12210
4-OH JWH-018 (JWH-018 4-hydroxyindole metabolite)9
JWH 122 6-methylnaphthyl isomer7
AM-22337
JWH-081 5-methoxynaphthyl isomer6.5
JWH-0306
JWH-081 7-methoxynaphthyl isomer (JWH-164)5
JWH-398 5-chloronaphthyl isomer5
AM-6945
*LOD is standardised to this compound