Synthetic Cannabinoids (JWH-250/RCS-8)

JWH-250 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid and peripheral cannabinoid receptors. JWH-250 has been identified as a component of several different ‘herbal incense’ products often marketed as ‘not for human consumption’. Belonging to the synthetic cannabinoid receptor agonists (SCRAs) category of drugs, JWH-250 has similar effects to those of THC. The quantity of JWH-250 within a package can vary significantly, increasing the likelihood of overdose as users are not fully aware of what is contained inside these herbal products. Reported effects of overdose include tachycardia, hypertension, agitation, hallucinations, minor elevation of blood glucose, hypokalemia and vomiting.

Product Number: SC3503

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AnalyteLODMatricesCompoundsCross Reactivity %
Synthetic Cannabinoids (JWH-250/RCS-8)0.39 ng/mLWhole Blood, Post Mortem Blood, UrineJWH-250100
JWH-250 N-(4-Hydroxypentyl) metabolite304
JWH-250 N-(5-Hydroxypentyl) metabolite290
JWH-250 N-(5-Carboxbutyl) metabolite111
JWH-250 N-(5-carboxypentyl) metabolite90
N-Desalkyl JWH-25084
JWH-25126
RCS-823
JWH-20317
JWH-250 5-Hyrdroxyindole metabolite3
RCS-8 3-methoxy Isomer (JWH-302)<1
RCS-8 4-methoxy isomer (JWH-201)<1
RCS-4<1
AM-2233<1
*LOD is standardised to this compound